This caricature of singer Sam Mayo might have inspired both Pee-wee and Jambi, but mostly Jambi. With the whole disembodied head thing.

The Dude, understandably, is Brad Pitt's fall fashion inspiration. An inspiration to us all, really.

I know: wtf, right? But Uma is totally Peggy.

PS: Uma, are you supposed to be playing a humanities professor in that outfit?

Was the creation of Amy Winehouse inspired by the cartoon version of Lydia Deetz from Beetlejuice?

Angelo Ackbar, anyone?

We all know Mr. Burns is Count Orlock from Nosferatu.

There's just something about Green Day drummer Tre Cool that makes me think he might have been the inspiration for Kyle's mom.

Vermont Senator Patrick Leahy and Tweedle-Dee.

Pope Benedict XVI and this thing from a Star Wars movie. I haven't seen that Star Wars business and avoid all things papal, but I'm sure they are both lovely men.

Quasimodo and Nathan Lane.

Dick Armitage and Thing.

Max Fischer as founder of the Yankee Racers and French photographer Jacques Henri Lartigue's brother. Named Zissou. Hmmm....

NBC News Chief Foreign Correspondent Andrea Mitchell and Yubaba from Spirited Away.

Improbably famous Seth Rogan and his much better looking doppelganger, Shrek.  Excellent call, Hilary!

Electric Mayhem lead guitarist Janice and Donatella Versace, who was clearly modeled after the much cooler muppet. Way to twinspot, Niani!

Blythe Danner -- shown here accepting her Teen Choice Award for Helen Keller 2: The Miracle Continues -- and Mokey Fraggle, flaunting her moveable eyelids. Good call, Kelly!

This person I know about for some reason Chris Brown and the self-proclaimed Boys of Rock and Roll, Alvin and The Chipmunks (mostly Alvin). Where's your giant turtleneck tunic, Chris?

This pork production and Bowser. Specifically, Bowser from Super Mario All Stars.

Walter Sobchak and Kirby. This Kirby image was found by my friend Zoe, and I'm pretty sure this is intentional. Do you see what happens, Kirby?